2015年韩国中东呼吸综合征疫情流行病学特征分析

目的 分析2015年韩国中东呼吸综合征(MERS)疫情的流行特征, 利于中国医疗卫生业务人员了解相关信息。方法 收集韩国政府、WHO等官方网站及韩国权威媒体信息, 进行疫情流行特征相关分析。结果 2015年5月20日至7月13日韩国共报告186例MERS确诊病例, 其中死亡36例。除2例可能为家庭内感染外, 其余病例均在医疗机构相关场所感染。首发病例1例, 二代病例29例、三代病例125例、四代病例25例, 6例代数不详。5个道(市)11个区域的16家医院报告了病例, 病例中包括39名医院工作人员。病例年龄M=55岁, 男性占60%。死亡病例年龄M=70岁, 男性占67%;78%的死亡病例有慢性基础性疾病。除首发病例外, 有12例发生了续发病例, 其中1例传播了84例。中国5月29日确诊1例韩国输入病例, 未发生二代病例。从韩国病例和中国输入性病例中获得的病毒与从中东地区获得的病毒相比无明显变化。结论 2015年韩国MERS疫情特点和传播模式与以往中东地区暴发疫情类似。     

Prepregnancy body mass index and gestational weight gain with the outcome of pregnancy: a 13-year study of 292,568 cases in China

Purpose

We aimed to investigate the combined associations of prepregnancy body mass index (BMI) and gestational weight gain (GWG) with pregnancy outcomes in Chinese women.

Methods

Data for 292,568 singleton term pregnancies were selected from 1993 to 2005 based on the Perinatal Health Care Surveillance System, with anthropometric measurements being collected prospectively. Prepregnancy BMI was categorized according to the definitions of the World Health Organization (WHO). Total GWG was categorized into four groups. Adjusted associations of prepregnancy BMI and GWG with outcomes of interest were estimated using logistic regression analyses. GWG was categorized as below, within and above the Institute of Medicine (IOM) (2009) recommendations.

Results

Maternal overweight and high GWG or GWG above the IOM recommendation were associated with hypertensive disorders complicating pregnancy, cesarean delivery, macrosomia and large-for-gestational-age (LGA) infants. Maternal underweight and low GWG or GWG below the IOM recommendation were risk factors for low-birth-weight (LBW) and small-for-gestational-age (SGA) infants. Moreover, being overweight [odds ratio (OR) 1.2, 95?% confidence interval (CI) 1.0–1.3) and having a low weight gain (OR 1.1, 95?% CI 1.0–1.1) increased the risk of newborn asphyxia.

Conclusion

Being overweight/obese and having a high weight gain, as well as being underweight and having a low weight gain, were associated with increased risks for adverse pregnancy outcomes in Chinese women.